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Recent research has found that a gene variant may predict naltrexone treatment success for alcoholism. About 50% of patients of Asian descent have a particular mutation which makes them more likely to benefit from naltrexone, in contrast to about 20% of Caucasians and less than 5% of African Americans, said lead study author Lara Ray, an assistant professor of psychology and director with the UCLA Addictions Laboratory. The findings are still available online ( inside the journal Neuropsychopharmacology and will be published within an upcoming print edition with the journal. Using two separate drugs to lose weight can be very effective you can find combinations while watching FDA now awaiting approval. When dealing with fat loss and the people who go through it you should err on the side of caution and let the FDA do its job and demand some investigation be done in order that the public knows the side effects and hazards of the medications before we bring them. Keep in mind that drug companies are in business to generate income and that they would say almost anything to keep people on the medications. Researchers found out that participants taking this drug to get a year, dropped excess weight within one month and have kept the body weight off throughout the 56 weeks of the study. Contrave can be a combination of the drugs naltrexone and bupropion, which appears to reflect a new trend of weight-loss drugs which are made up of many active ingredient, which might make them more efficient and safer. Combo-pilling could be the newest fad or better yet the newest ahead under scrutiny and for that reason it is just more publicly known recently, comb-pilling for losing weight has been around since the eighties. The biggest reason that using a combination of pills has become popular could be the fact that by right now there are no long term prescription weightloss pills that have been approved by the FDA besides orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications although some people might of the combinations are already rejected or have yet to be approved by the FDA. Seizures are a side effect with Contrave and must not be taken in individuals with seizure disorders. The drug can also raise blood pressure levels and heart rate, and really should not be used in those with a history of cardiac arrest or stroke in the last six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy with the drug. The FDA also warned that Contrave can raise blood pressure and pulse rate and must not be used in patients with uncontrolled high blood pressure levels, as well as by you are not heart-related and cerebrovascular (circulation system dysfunction impacting the brain) disease. Patients with a history of heart attack or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes having a boxed warning to alert medical researchers and patients to the increased probability of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for quitting smoking. An independent report published by Gant Daily in April also stated that naltrexone also utilizes kleptomaniacs and gambling addicts, too. Citing research from the University of Minnesota School of Medicine, Gant Daily reported the drug works on kleptomaniacs and chronic gamblers just as with alcohol and opioid addicts'by blocking the effects of endorphins, that your brain releases when experiencing craving or compulsions.